高密度超多芯连接器组装工艺研究

为了适应电子产品小型化和高密度集成要求,高密度超多芯连接器被广泛使用。由于其引线数量多、间距小、焊接间隙微小等原因,传统手工焊接方法很难满足其焊接质量要求。对高密度超多芯连接器组装方法进行了研究。通过焊接工艺优化,成功实现了焊接间隙0.08 mm的LRMS系列连接器可靠焊接,一次组装合格率达到98%以上。     

一种船舶电力参数测量仪的设计

针对船舶电力系统运行工况的复杂性和运行环境的特殊性所造成的电力参数测量精确度不高的问题,利用汉宁窗加权的递推DFT算法对电力参数进行分析和研究。从理论上分析了算法的可行性,通过仿真得到了较高的测量精度。经由嵌入式STM32F407和AD7656的综合设计,完成了一种船舶电力参数测量仪的研制,并结合电能质量谐波检测进行实验,利用标准信号源对测量仪的精度进行了测试。测试结果表明,设计的船舶电力参数测量仪检测精度高,可以应用于实际电力系统的参数测量。     

某铁矿强磁尾矿反浮选回收试验研究

针对我国西部某铁矿强磁选尾矿进行了反浮选回收铁资源的试验研究, 探讨了pH值、抑制剂可溶性淀粉用量、阳离子捕收剂十二胺用量对浮选指标的影响。结果表明, 在矿浆pH=10、可溶性淀粉用量2 400 g/t、十二胺用量400 g/t条件下进行一粗一精(精选药剂用量减半)闭路反浮选, 可获得铁品位43.88%、回收率50.93%的铁精矿产品。     

CD34⁺ CD38^- subpopulation without CD123 and CD44 is responsible for LSC and correlated with imbalance of immune cell subsets in AML

Acute myeloid leukemia (AML) is regarded as a stem cell disease. However, no one unique marker is expressed on leukemia stem cells (LSC) but not on leukemic blasts nor normal hematopoietic stem cells (HSC). CD34⁺ CD38- with or without CD123 or CD44 subpopulations are immunophenotypically defined as putative LSC fractions in AML. Nevertheless, markers that can be effectively and simply held responsible for the intrinsical heterogeneity of LSC is still unclear. In the present study, we examined the frequency of three different LSC subtypes (CD34⁺ CD38^-, CD34⁺ CD38^- CD123⁺ , CD34⁺ CD38^- CD44⁺ ) in AML at diagnosis. We then validated their prognostic significance on the relevance of spectral features for diagnostic stratification, immune status, induction therapy response, treatment effect maintenance, and long-term survival. In our findings, high proportions of the above three different LSC subtypes were all significantly characterized with low complete remission (CR) rate, high relapse/refractory rate, poor overall survival (OS), frequent FLT3-ITD mutation, the high level of regulatory T cells (Treg) and monocytic myeloid-derived suppressor cells (M-MDSC). However, there was no significant statistical difference in all kinds of other clinical performance among the three different LSC groups. It was demonstrated that CD34⁺ CD38^- subpopulation without CD123 and CD44 might be held responsible for LSC and correlated with an imbalance of immune cell subsets in AML.     

MDA-TOEPGA: A novel method to identify miRNA-disease association based on two-objective evolutionary programming genetic algorithm

The association between miRNA and disease has attracted more and more attention. Until now, existing methods for identifying miRNA related disease mainly rely on top-ranked association model, which may not provide a full landscape of association between miRNA and disease. Hence there is strong need of new computational method to identify the associations from miRNA group view. In this paper, we proposed a framework, MDA-TOEPGA, to identify miRNAdisease association based on two-objective evolutionary programming genetic algorithm, which identifies latent miRNAdisease associations from the view of functional module. To understand the miRNA functional module in diseases, the case study is presented. We have been compared MDA-TOEPGA with several state-of-the-art functional module algorithm. Experimental results showed that our method cannot only outperform classical algorithms, such as K-means, IK-means, MCODE, HC-PIN, and ClusterONE, but can also achieve an ideal overall performance in terms of a composite score consisting of f1, Sensitivity, and Accuracy. Altogether, our study showed that MDA-TOEPGA is a promising method to investigate miRNA-disease association from the landscapes of functional module.     

缺乏地质封存条件地区开展CCUS项目集群化建设的可行性研究:以江西省为例

碳捕集、利用与封存（CCUS）技术是我国实现碳达峰和碳中和目标的关键技术。良好的 源汇匹配条件是CCUS项目部署的重要先决条件。然而我国存在一些缺乏地质封存条件的地区，虽然区域内拥有较多工业排放源，但缺少近距离的潜在封存地，影响了企业的投资决策。CCUS项目的集群化建设可以通过共用CO2运输和封存设备，降低项目的整体成本，集群化建设能否推动缺乏地质封存条件地区CCUS项目的部署，需要进一步研究。以江西省为例，选取南昌市和萍乡市的7个公开披露碳排放信息的企业，分别开展年捕集量为 100万t的碳捕集项目，通过管网优化并选取江汉盆地为潜在封存地，建立成本分析模型 并计算单位减排成本。结果显示，虽然集群项目的运输距离长达513 km，但最终的CO2 减排成本仅为473.04元/t，而且还存在进一步下降的可能。在缺乏地质封存条件的地区开展CCUS项目的集群化建设，可以成为利用CCUS技术助力碳中和的一个重要方式。     

氨基羟基脲还原反萃高浓度Pu(Ⅳ)

采用氨基羟基脲（HSC）的硝酸水溶液研究了从30%（体积分数，下同）TBP/煤油中还原反萃高浓度四价钚（Pu（Ⅳ））的性能，并与羟胺-肼（HAN-HN）、N,N-二甲基羟胺-单甲基肼（DMHAN-MMH）在钚净化浓缩循环中反萃行为进行了对比。结果表明：在一定HSC浓度下，适当延长相接触时间、减小相比（o/a）、降低酸度和提高温度，均有利于Pu（Ⅳ）的还原反萃。HSC作为还原反萃剂，可以有效实现30%TBP/煤油中高浓钚的反萃，反萃效果较其它几种还原剂更好，有望在先进二循环流程的钚净化浓缩工艺中得到应用。     

35克素牛排单片重量控制方案探究

目的探究制定公司畅销产品大豆蛋白类食品35克素牛排的重量控制方案。方法研发人员通过查阅相关资料、采集生产与管理人员的意见、跟踪生产全程等手段获取实验方向,并通过小实验改变工艺条件和生产试验进一步验证工艺条件,探寻出了35克素牛排在生产过程中的重量变化规律、重量不稳定的主要原因及改进措施。结果 35克素牛排的单片重量与产品卤制工序呈影响极显著,与原材料重量、油炸工序差异显著。结论原材料控制在11克以上,油炸时间2分钟,最佳卤制时间10分钟,产品的单片重量合格率提高到90%以上。     

白炭黑粒子间距对天然橡胶复合材料性能的影响

分别采用不同分子链长度的改性剂乙二醇二缩水甘油醚、丁二醇二缩水甘油醚、己二醇二缩水甘油醚和聚乙二醇二缩水甘油醚(PEGDGE)对白炭黑进行隔离改性,研究改性白炭黑对天然橡胶(NR)复合材料性能的影响。结果表明:与未改性白炭黑填充的NR复合材料相比,改性白炭黑填充的NR复合材料的t10和t90缩短,FL和储能模量(G′)减小,硬度降低,拉伸强度、拉断伸长率和撕裂强度提高;当改性剂为PEGDGE(回转半径为1.11 nm)时,改性白炭黑的粒子间距最大,分散性最好,NR复合材料的交联密度最大,G′和损耗因子最小,物理性能最佳。     

时效处理对高频感应熔覆TiC/Ni复合涂层的组织及性能影响

为了改善抽油杆材料的表面性能,采用高频感应熔覆技术在其表面制备了TiC/Ni复合涂层。采用光学显微镜、扫描电镜(SEM)、能谱仪(EDS)、X射线衍射仪(XRD)等研究了涂层经固溶及不同时间时效处理后的显微组织及物相组成,并利用显微硬度计及摩擦磨损实验测试了时效后涂层的性能变化。结果表明:经固溶时效后的涂层并未出现明显缺陷,涂层主要以γ-Ni固溶体、Ni的化合物、CrB、碳化物以及δ相等硬质颗粒组成;时效后涂层的最大硬度达到928.2 HV0.2,相比时效前提高了4%,最低磨损量为48.9 mg,比基材减少了62%,在时效4 h后,涂层的综合性能最好。